A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF DECONGESTANT-ANTIHISTAMINE FOR THE TREATMENT OF SINUSITIS IN CHILDREN

We studied the effectiveness of nasal decongestant-antihistamine in tr eating acute sinusitis in children. All subjects received oral amoxici llin for 14 days, Subjects randomized to the decongestant-antihistamin e group received nasal oxymetazolone and oral syrup containing bromphe niramine and phenylpropanolamine. Controls received placebo nasal sali ne and oral syrup, In both groups symptoms resolved quickly, and radio graphs improved significantly. Responses to treatment were similar bet ween the two groups. Water's radiographs of the maxillary sinuses prov ed reliable in the assessment of the degree of sinus involvement, We c onclude that decongestant-antihistamine need not be given to the child with acute maxillary sinusitis.