G. Rushton et al., THE SPATIAL RELATIONSHIP BETWEEN INFANT-MORTALITY AND BIRTH-DEFECT RATES IN A US CITY, Statistics in medicine, 15(17-18), 1996, pp. 1907-1919
The spatial patterns of infant mortality and birth defect rates in the
Des Moines, Iowa, urban region are described as a contoured surface b
ased on the punctual kriging of address-matched vital statistics recor
ds from The Iowa Department of Public Health. Areas defined as having
high rates are shown to be sensitive to the size of the spatial filter
ing units. There is no correlation between infant mortality and birth
defect rates in the region. The significance of areas with high rates
is determined by a Monte Carlo simulation procedure, One area of high
infant mortality is found in the region, which contrasts with many sma
ller areas with high birth defect rates in the region. The observed bi
rth defect rate pattern is consistent with the hypothesis that each bi
rth was equally likely to result in a birth defect, while the infant m
ortality pattern is unlikely to be the result of such an equal likelih
ood process.