TISSUE DISTRIBUTION OF EPSTEIN-BARR-VIRUS GENOTYPES

Authors
CHEN HL LUNG ML CHAN KH GRIFFIN BE NG MH
Citation
Hl. Chen et al., TISSUE DISTRIBUTION OF EPSTEIN-BARR-VIRUS GENOTYPES, Journal of virology, 70(10), 1996, pp. 7301-7305
Citations number
29
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
70
Issue
10
Year of publication
1996
Pages
7301 - 7305
Database
ISI
SICI code
0022-538X(1996)70:10<7301:TDOEG>2.0.ZU;2-X
Abstract
The genome of naturally occurring Epstein-Barr virus contains either t wo or three copies of a 29-bp tandem repeat sequence in the first intr on of the BZLF gene. These genotypes differ markedly in their distribu tion between blood and epithelial tissues, presumably because they hav e adapted to separate life cycles in these sites. The genotype prevale nt in the blood also appears to be better able to transform B lymphocy tes.