Background: On the basis of recent social and behavioral research, tog
ether with more than a decade of practical experience in countries aro
und the world, an important shift has begun to take place in the model
s or paradigms that have been developed to understand and respond to t
he HIV/AIDS epidemic. A growing awareness of the complex social, cultu
ral, political and economic forces shaping the epidemic - and, in part
icular, of the link between the social injustice and increased vulnera
bility to HIV infection - has led to the reformation of both theory an
d practice aimed at responding to AIDS and meeting the needs of those
most affected by the epidemic. HIV/AIDS prevention: The focus of HIV/A
IDS prevention efforts has increasingly shifted from models aimed at c
hanges in individual risk behavior to models aimed at community mobili
zation. An earlier emphasis on information-based educational campaigns
has given way to intervention programs aimed at enablement and empowe
rment in the face of the epidemic. Perspectives: These developments ha
ve been linked to a new awareness of the fundamental connection betwee
n public health and human rights, and to a new understanding of the fi
ght against AIDS as part of a much broader process of social change ai
med at redressing structures of inequality, intolerance and injustice.