(+ TA-METHYL-6-ALPHA-PHENYLTETRAHYDRO-2H-PYRAN-2-ONE/

Authors
FALLON GD LAWRENCE RM PERLMUTTER P
Citation
Gd. Fallon et al., (+ TA-METHYL-6-ALPHA-PHENYLTETRAHYDRO-2H-PYRAN-2-ONE/, Acta crystallographica. Section C, Crystal structure communications, 52, 1996, pp. 2067-2069
Citations number
7
Categorie Soggetti
Crystallography
Journal title
Acta crystallographica. Section C, Crystal structure communications → ACNP
ISSN journal
01082701
Volume
52
Year of publication
1996
Part
8
Pages
2067 - 2069
Database
ISI
SICI code
0108-2701(1996)52:<2067:(T>2.0.ZU;2-I
Abstract
The structure determination of the title compound, dimethyl (+/-)-3 be ta-methyl-2-oxo-6 alpha-phenyl-3,4,5,6-te hydro-2H-pyran-3 alpha, 5 al pha-dicarboxylate, C16H18O6. Unequivocally establishes its relative st ereochemistry. The results provide strong support for the proposal tha t enolates derived from cis-5,6-disubstituted tetrahydro-2H-pyran-2-on es react very selectively with electrophiles trans to the C(5) and C(6 ) substituents.