FORMYLATION VERSUS ALKYLATION OF SECONDARY-AMINES IN DMF

Authors
BARRETT DMY KAHWA IA WILLIAMS DJ
Citation
Dmy. Barrett et al., FORMYLATION VERSUS ALKYLATION OF SECONDARY-AMINES IN DMF, Acta crystallographica. Section C, Crystal structure communications, 52, 1996, pp. 2069-2071
Citations number
9
Categorie Soggetti
Crystallography
Journal title
Acta crystallographica. Section C, Crystal structure communications → ACNP
ISSN journal
01082701
Volume
52
Year of publication
1996
Part
8
Pages
2069 - 2071
Database
ISI
SICI code
0108-2701(1996)52:<2069:FVAOSI>2.0.ZU;2-F
Abstract
di-1,2-ethanediyl)bis[1H-isoindole-1,3-(2H)-dione] (1), C21H17N3O5, is a product of a slow formylation reaction between refluxing DMF and 2, 2'-(iminodi-1 ,2-ethanediyl)bis[1H-isoindole-1,3(2H)-dione] (DPDA) whi ch appears to be more efficient than the competing base-promoted alkyl ation with tris(chloroethyl)amine. The molecules adopt a folded confor mation and pack efficiently to form sheets (in the a and c directions) having a 'W in W' and 'M in M' motif running along the c direction.