ON THE SYNTHESIS OF NAPHTHOQUINONYL HETEROCYCLIC AMINO-ACIDS

Authors
SHRESTHADAWADI PB BITTNER S FRIDKIN M RAHIMIPOUR S
Citation
Pb. Shresthadawadi et al., ON THE SYNTHESIS OF NAPHTHOQUINONYL HETEROCYCLIC AMINO-ACIDS, Synthesis, (12), 1996, pp. 1468
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
12
Year of publication
1996
Database
ISI
SICI code
0039-7881(1996):12<1468:OTSONH>2.0.ZU;2-6
Abstract
L-Histidine, N-alpha-cbz-L-histidine, L-tryptophan and L-proline react with 1,4-naphthoquinone or 2,3-dichloro-1,4-naphthoquinone to afford modified N-quinonyl amino acids. With free alpha-amino acids, the quin one moiety is attached to the alpha-amino group. With blocked alpha-am ino acids, the quinone moiety is attached to the alpha-amino group. Wi th blocked alpha-amino acids the quinone moiety is attached to the het erocyclic nitrogen atom.