AN IMPROVED SYNTHESIS OF DICHLOROALKYLPHOSPHONATES, CHLOROALKYNES ANDTERMINAL ALKYNES VIA DIETHYL DICHLOROMETHYLPHOSPHONATE

Authors
CARRAN J WASCHBUSCH R MARINETTI A SAVIGNAC P
Citation
J. Carran et al., AN IMPROVED SYNTHESIS OF DICHLOROALKYLPHOSPHONATES, CHLOROALKYNES ANDTERMINAL ALKYNES VIA DIETHYL DICHLOROMETHYLPHOSPHONATE, Synthesis, (12), 1996, pp. 1494
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
12
Year of publication
1996
Database
ISI
SICI code
0039-7881(1996):12<1494:AISODC>2.0.ZU;2-#
Abstract
Diethyl 1,1-dichloromethylphosphonate (2) was synthesised in good yiel d from the reduction of 1,1,1-trichloromethylphosphonate (1) with i-C3 H7MgCl and subsequent hydrolysis. The reactivity of 2 towards alpha-al kylation and its utility in the synthesis of chloroalkynes and termina l alkynes was investigated.