Background and aims of the study: Heart valve replacement can result i
n serious complications. Therefore, It is important, in decision makin
g regarding the choice of valves to know the cost of such complication
s. Methods: Complications were defined according to guidelines propose
d by the Society of Thoracic Surgeons. They included valve thrombosis,
embolism, hemorrhage due to anticoagulation, non-structural dysfuncti
on, structural deterioration and endocarditis. The costs of the pre-ad
mission assessment, acute inpatient stay, inpatient physician fees, po
st-discharge and out-patient physician fees were estimated for each co
mplication to determine the average total cost in 1995 US dollars. Cos
t inputs were obtained from existing Massachusetts databases and Medic
are fee schedules. Results: The costs of managing valve thrombosis, en
docarditis and non-structural dysfunction were all estimated to exceed
$30,000 for a single event, The costs of acute management of embolism
and anticoagulant-related hemorrhage were between $8,000 and $11,500.
However, it is of note that managing the sequelae of an embolism was
calculated to be greater than $70,000 over 25 years. The greatest cont
ributor to the average cost of treating a complication was determined
to be the in-patient facility cost. Conclusions: Complications related
to heart valve replacement can be very costly to manage in both the s
hort term and the long term.