Purpose: Our goal was to describe the pulmonary parenchymal manifestat
ions of Takayasu arteritis visualized on CT. Method: We assessed the C
T findings for the pulmonary parenchyma in 25 patients with Takayasu a
rteritis and compared them with those visualized by pulmonary angiogra
phy (n = 20) and radionuclide perfusion scintigraphy (n = 19) Results:
A review of the CT scans revealed a total of 33 low attenuation areas
in the lung (II patients), subpleural reticulolinear changes (12 pati
ents), and pleural thickening (9 patients). The low attenuation areas
were preferentially seen in patients with pulmonary arteritis and corr
esponded to pulmonary angiographic staining and scintigraphic perfusio
n defects. No significant cor relation was found between other CT find
ings and pulmonary arteritis. Conclusion: The findings suggest that pu
lmonary low attenuation areas observed on CT represent regional hypope
rfusion due to pulmonary arteritis. We speculate that pulmonary thromb
oembolism may contribute to other CT findings for the pleura and adjac
ent lung.