Eg. Pearson et al., ATYPICAL PNEUMONIA ASSOCIATED WITH RYEGRASS STAGGERS IN CALVES, Journal of the American Veterinary Medical Association, 209(6), 1996, pp. 1137
A group of 6- to 8-month-old carves developed head tremors, stiff gait
, and staggering after consuming ryegrass straw that contained 3,711 m
u g of lolitrem-B/kg. Signs were consistent with ryegrass staggers syn
drome. At necropsy, all calves examined had atypical interstitial pneu
monia, with marked emphysema and bullae, Infectious organisms and pneu
motoxins were not identified. Experimentally, feeding the same ryegras
s straw to age-matched calves induced similar neurologic signs, but di
d not result in pneumonic lesions. The high concentration of lolitrem-
B in the straw or other, undefined factors, such as feed changes, may
have contributed to the atypical interstitial pneumonia in the natural
ly exposed calves.