Vd. Poryvayev et al., EFFECTS OF THE COMPONENTS OF VIRUS-CONTAI NING ALLANTOIC FLUID ON THESTABILITY OF INFLUENZA-VIRUS UPON STORAGE, Voprosy virusologii, 41(3), 1996, pp. 126-129
Effects of allantoic fluid fractions (isolated by sedimentation and ge
l chromatography) on inactivation of influenza virus and lipid peroxid
ation in viral envelopes and phospholipid liposomes indicate the prese
nce of both components with prooxidant effects enhancing inactivation
and of endogenous antioxidants stabilizing the viral activity. The hyp
othesized ''lipid'' mechanism of inactivation (suggesting activation o
f lipid peroxidation in viral envelopes followed by inactivation of vi
ral nucleoprotein) permits a satisfactory interpretation of viral mate
rial inactivation.