Background We wished to determine the incidence, reasons, casts, and p
redictors of cardiac-related hospital readmission in patients with tie
red-therapy implantable defibrillators. Hospital readmission in patien
ts with defibrillators reduces their quality of life and increases the
cost associated with such therapy. Methods and Results We retrospecti
vely studied 65 consecutive local patients (median age, 67 years; medi
an ejection fraction, 0.34) who underwent tiered-therapy defibrillator
implantation at this institution. Patients were followed for a median
of 19 months (interquartile range, 10 to 27 months). The cause, durat
ion, costs, and predictors of cardiac-related rehospitalizations were
analyzed. There were 76 cardiac admissions for 34 patients. The rate o
f cardiac-related hospital readmission was 0.72 per patient-year of fo
llow-up. Arrhythmia-related admissions accounted for 33 of such admiss
ions in 23 patients. Actuarial freedom from cardiac-related admissions
was 0.57 and 0.40 at 1 and 2 years, respectively. The median length o
f stay for hospital readmissions was 5 days (interquartile range, 3 to
8 days). The median cost per admission was $5842 (interquartile range
, $3549 to $12 170). The time to first readmission and the total rehos
pitalization time per year of follow-up were associated with a poor pr
eimplant New York Heart Association functional class. Readmission for
cardiac arrhythmias was nor predicted by clinical parameters. Conclusi
ons Rehospitalization For cardiac reasons is common in patients receiv
ing implantable defibrillators and is responsible for substantial reso
urce consumption. The need for readmission for arrhythmia-related reas
ons cannot be predicted by clinical parameters at the time of device i
mplantation.