A NOVEL BETA-GALACTOSIDE-BINDING LECTIN IN CULTURED MURINE LYMPHOCYTIC-LEUKEMIA CELLS

Authors
MAI A JUNG SK TACHIKAWA H FUJIMOTO D
Citation
A. Mai et al., A NOVEL BETA-GALACTOSIDE-BINDING LECTIN IN CULTURED MURINE LYMPHOCYTIC-LEUKEMIA CELLS, Journal of Biochemistry, 120(3), 1996, pp. 478-480
Citations number
21
Categorie Soggetti
Biology
Journal title
Journal of Biochemistry → ACNP
ISSN journal
0021924X
Volume
120
Issue
3
Year of publication
1996
Pages
478 - 480
Database
ISI
SICI code
0021-924X(1996)120:3<478:ANBLIC>2.0.ZU;2-H
Abstract
Using affinity chromatography on lactosyl-Sepharose, a beta-galactosid e-binding protein of 38 kDa was detected in mouse L1210 lymphocytic le ukemia cells, Immunoblotting analysis revealed that it is distinct fro m any known larger molecular weight galectin. The partial amino acid s equences of the 35 kDa protein indicated that it is a novel member of the galectin family. This 38 kDa lectin is expressed in lymphocytic ce ll lines but not macrophage-like cell lines.