Tear secretion, tear film stability, and meibomian gland function (plu
gging, volume, and thickness) were assessed;in patients with psoriasis
vulgaris (n = 70), As compared to that of the healthy controls (n = 1
25) mean Schirmer I value of psoriatic patients was found to be in nor
mal ranges, whereas tear film break-up time was significantly lowered.
When evaluating meibomian gland function, psoriatic patients were fou
nd to have higher plugging and thickness indices but a normal volume o
f meibomian gland secretion, These findings suggested an obstructive t
ype of meibomian gland dysfunction in psoriatic patients which might r
esult from increased turnover of the epithelia lining the meibomian gl
and duct.