The deposition of immunoglobulin (Ig) light chains after renal transpl
antation most commonly occurs as a manifestation of recurrent multiple
myeloma or recurrent light chain nephropathy. We report the developme
nt of de novo light chain deposition disease (LCDD) in a cadaveric ren
al transplant recipient 16 years after transplantation with no evidenc
e of prior multiple myeloma or LCDD and no current evidence of myeloma
or lymphoproliferative malignancy. (C) 1996 by the National Kidney Fo
undation, Inc.