OXIDATION OF N-(4-METHOXYBENZYL)-2-PYRROLIDINONES TO N-(4-METHOXYBENZOYL)-2-PYRROLIDINONES - RAPID ENTRY TO OPTICALLY-ACTIVE ANIRACETAM ANALOGS

Authors
MCALONAN H MURPHY JP STEVENSON PJ TREACY AB
Citation
H. Mcalonan et al., OXIDATION OF N-(4-METHOXYBENZYL)-2-PYRROLIDINONES TO N-(4-METHOXYBENZOYL)-2-PYRROLIDINONES - RAPID ENTRY TO OPTICALLY-ACTIVE ANIRACETAM ANALOGS, Tetrahedron, 52(38), 1996, pp. 12521-12528
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
38
Year of publication
1996
Pages
12521 - 12528
Database
ISI
SICI code
0040-4020(1996)52:38<12521:OONTN>2.0.ZU;2-M
Abstract
Oxidation of readily available N-(4-methoxybenzyl)-5-alkylpyrrolidin-2 -ones to the corresponding N-(4-methoxybenzoyl)-5-alkylpyrrolidin-2-on es gives direct access to enantiomerically pure 5-alkyl analogues of t he cognition activating agent Aniracetam. Copyright (C) 1996 Elsevier Science Ltd