A. Tait et al., SYNTHESIS AND FREE-RADICAL SCAVENGING ACTIVITY OF ,1-DIOXIDE-3-YL)-2,6-BIS(1,1-DIMETHYLETHYL)PHENOLS, Tetrahedron, 52(38), 1996, pp. 12587-12596
,1-dioxide-3-yl)-2,6-bis(1,1-dimethylethyl)phenols (1-11) were prepare
d by cyclization of the corresponding lethyl)-4-hydroxy-N-2-(sulphamoy
lphenyl)benzamides (12-22). Compounds 1-22 were tested as free radical
scavengers by reaction with DPPH using UV and ESR spectrometry and th
e formation of stable phenoxy radicals by their oxidation with lead te
traacetate was also studied. Copyright (C) 1996 Published by Elsevier
Science Ltd