Authors
Citation
C. Delcampo et al., DESIGN, SYNTHESIS AND EVALUATION OF A CHIRAL PROPRANOLOL SELECTOR, Tetrahedron : asymmetry, 7(9), 1996, pp. 2627-2631
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
ISSN journal
09574166
Volume
7
Issue
9
Year of publication
1996
Pages
2627 - 2631
Database
ISI
SICI code
0957-4166(1996)7:9<2627:DSAEOA>2.0.ZU;2-A
Abstract
Synthesis of enantiomerically pure (S)-(-)-propranolol, the most activ
e of the widely used beta-blockers adrenergics, was achieved using a n
ew chiral stationary phase (CSP) for the separation of a derivative. T
his simple methodology shows a significant improvement in the separati
on of the enantiomers of a propranolol derivative over previous method
s. Copyright (C) 1996 Published by Elsevier Science Ltd