A. Tait et al., STEREOSPECIFIC SYNTHESIS OF IADIAZINE-1,1-DIOXIDE-3-YL)THIO]-2-METHYLPROPANOIC ACIDS, Tetrahedron : asymmetry, 7(9), 1996, pp. 2703-2706
iadiazine-1,1-dioxide-3-yl)thio]-2-methylpropanoic acids were synthesi
zed from the corresponding 3-mercaptoderivatives by alkylation with () (R)- and (-) (S)-3-bromo-2-methylpropanoic acid methyl ester. The nu
cleophilic substitution takes place with complete maintenance of the e
nantiomeric purity. Copyright (C) 1996 Elsevier Science Ltd