SYNTHESIS AND PROPERTIES OF A BIOCOMPATIBLE ANALOG FOR BETA-TURN PROTEIN STRUCTURAL MOTIFS BASED ON 5-AMINO-3-PENTYNOIC ACID

Authors
HARTZOULAKIS B RUTHERFORD TJ RYAN MD GANI D
Citation
B. Hartzoulakis et al., SYNTHESIS AND PROPERTIES OF A BIOCOMPATIBLE ANALOG FOR BETA-TURN PROTEIN STRUCTURAL MOTIFS BASED ON 5-AMINO-3-PENTYNOIC ACID, Tetrahedron letters, 37(38), 1996, pp. 6911-6914
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
38
Year of publication
1996
Pages
6911 - 6914
Database
ISI
SICI code
0040-4039(1996)37:38<6911:SAPOAB>2.0.ZU;2-Z
Abstract
5-Amino-3-pentynoic acid, a new 'lightly' constrained amino acid surro gate for glycyl-glycine and model for dipeptide homologues was prepare d from propargylamine and methods were devised for its incorporation i nto linear oligopeptides through both C- and N-terminal extension. Cop yright (C) 1996 Elsevier Science Ltd