ORGANOMETALLIC NUCLEOPHILIC RING-OPENING OF ENDO PEROXIDES

Authors
SCHWAEBE MK LITTLE RD
Citation
Mk. Schwaebe et Rd. Little, ORGANOMETALLIC NUCLEOPHILIC RING-OPENING OF ENDO PEROXIDES, Tetrahedron letters, 37(37), 1996, pp. 6635-6638
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
37
Year of publication
1996
Pages
6635 - 6638
Database
ISI
SICI code
0040-4039(1996)37:37<6635:ONROEP>2.0.ZU;2-M
Abstract
The reaction of symmetrical and unsymmetrical endo peroxides with orga nometallic reagents affords hydroxy ethers. Primary, secondary, vinyl and aryl groups can be transferred with alkyllithium and Grignard reag ents providing the best yields, organozincates, moderate. This demonst rates a new reactivity pattern for endoperoxides and provides a novel method for the formation of a variety of useful building blocks. Copyr ight (C) 1996 Elsevier Science Ltd