NOSTOCYCLIN, A NOVEL 3-AMINO-6-HYDROXY-2-PIPERIDONE-CONTAINING CYCLICDEPSIPEPTIDE FROM THE CYANOBACTERIUM NOSTOC SP

Authors
KAYA K SANO T BEATTIE KA CODD GA
Citation
K. Kaya et al., NOSTOCYCLIN, A NOVEL 3-AMINO-6-HYDROXY-2-PIPERIDONE-CONTAINING CYCLICDEPSIPEPTIDE FROM THE CYANOBACTERIUM NOSTOC SP, Tetrahedron letters, 37(37), 1996, pp. 6725-6728
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
37
Year of publication
1996
Pages
6725 - 6728
Database
ISI
SICI code
0040-4039(1996)37:37<6725:NAN3C>2.0.ZU;2-Y
Abstract
Nostocyclin, a novel 3-amino-6-hydroxy-2-piperidone-containing cyclic peptide was isolated from a hepatotoxic strain of cyanobacterium Nosto c sp. Nostocyclin is non-toxic in acute in vivo bioassays, but inhibit s protein phosphatase-l activity at high concentration in vitro. Copyr ight (C) 1996 Elsevier Science Ltd