Y. Nagase et al., ELECTROENCEPHALOGRAPHY IN SCHIZOPHRENIC-PATIENTS - COMPARISON BETWEENNEUROLEPTIC-NAIVE STATE AND AFTER TREATMENT, Biological psychiatry, 40(6), 1996, pp. 452-456
Electroencephalography of 12 schizophrenic patients was recorded in a
neuroleptic-naive state and after 6.2 +/- 1.1 months of treatment, whe
n they were on medication and in partial remission. Compared with age-
and sex-matched controls, the neuroleptic-naive schizophrenics had le
ss alpha 2 power. In the medicated state, alpha 2 power and slew-wave
power were reduced as compared with the neuroleptic-naive state. The r
eduction in alpha 2 power may occur from the early stage of the diseas
e and progress even though the patients are medicated and clinically i
mproved.