REGIONAL 3-DIMENSIONAL GEOMETRY OF THE NORMAL HUMAN LEFT-VENTRICLE USING CINE COMPUTED-TOMOGRAPHY

Citation
J. Lessick et al., REGIONAL 3-DIMENSIONAL GEOMETRY OF THE NORMAL HUMAN LEFT-VENTRICLE USING CINE COMPUTED-TOMOGRAPHY, Annals of biomedical engineering, 24(5), 1996, pp. 583-594
Citations number
32
Categorie Soggetti
Engineering, Biomedical
ISSN journal
00906964
Volume
24
Issue
5
Year of publication
1996
Pages
583 - 594
Database
ISI
SICI code
0090-6964(1996)24:5<583:R3GOTN>2.0.ZU;2-G
Abstract
The aim of this study is to provide accurate three-dimensional measure ments of left ventricular geometrical indices in relation to regional myocardial function. The analysis of the three-dimensional regional ge ometry and function of left ventricles of ten normal human volunteers is based on three-dimensional reconstructions of the left ventricle fr om cine computed tomography images, at end diastole and end systole, d emonstrating normal left ventricular spatial, geometrical, and functio nal variability. Regional wall thickness, curvature and surface normal s, as well as wall thickening and endocardial wall motion, are calcula ted and mapped for the entire left ventricle. The circumferential asym metry of the left ventricle is reflected by the smaller circumferentia l and meridional curvatures at the septum. Thickening is highest at th e anterior and lateral walls. Longitudinally, circumferential curvatur e increases toward the apex, whereas both wall thickness and wall thic kening at end systole are largest at the midventricular level, decreas ing toward the apex and base. This study describes the circumferential and apex-to-base variations in regional left ventricular geometric pa rameters of the normal human left ventricle, using three-dimensional i maging and analysis.