DIMETHYL-SULFOXIDE RATHER THAN SUPEROXIDE IS THE REACTIVE SPECIES IN HORSERADISH-PEROXIDASE - KO2 DIMETHYL SULFOXIDE SYSTEM/

Authors
GEBICKA L GEBICKI JL
Citation
L. Gebicka et Jl. Gebicki, DIMETHYL-SULFOXIDE RATHER THAN SUPEROXIDE IS THE REACTIVE SPECIES IN HORSERADISH-PEROXIDASE - KO2 DIMETHYL SULFOXIDE SYSTEM/, Biochemistry and molecular biology international, 37(5), 1995, pp. 1021-1026
Citations number
16
Categorie Soggetti
Biology
Journal title
Biochemistry and molecular biology international → ACNP
ISSN journal
10399712
Volume
37
Issue
5
Year of publication
1995
Pages
1021 - 1026
Database
ISI
SICI code
1039-9712(1995)37:5<1021:DRTSIT>2.0.ZU;2-7
Abstract
It has been shown that dimethyl sulfoxide competes with the enzyme sub strate towards horseradish peroxidase compound I, but probably not tow ards horseradish peroxidase compound II. Dimethyl sulfoxide may hinder the reaction of superoxide with horseradish peroxidase compound II by modifying heme center. In this connection dimethyl sulfoxide is not r ecommended as a solvent in catalytic studies of horseradish peroxidase .