Analysis of meiotic pairing behavior in two XYY males presenting at su
bfertility clinic brings evidence that the abnormal mode of pairing ca
used by the presence of the extra Y chromosome, disturbs achievement o
f spermatogenesis resulting in severe oligoastheno-teratozoospermia. I
n contrast, the loss of the supernumerary Y before meiosis, allows ach
ievement and normal sperm production.