There are numerous measures of essential mineral element status, inclu
ding growth rate, tissue and physiological fluid concentrations, enzym
e concentrations and activities, chemical balance and mobilizable stor
es. For the adult human, blood and its specific nutrient concentration
s provide a useful but frequently inadequate index. The first limiting
biochemical system should provide the most valid index, but in many c
ases it is unknown or not readily measured. Chemical balance and mobil
izable stores provide valid measures but are difficult to determine. T
wo indices are infinitely more valuable than one and should be determi
ned if possible. More research is needed to establish valid indicators
of nutritional status for mineral elements.