W. Samborski et al., NEUROMODULATORS IN FIBROMYALGIA COMPARED WITH DEPRESSION (TENTATIVE COMMUNICATION), Aktuelle Rheumatologie, 21(5), 1996, pp. 253-256
Decreased levels of serotonin were found in fibromyalgia (n=60) and ma
jor depression (n=20) in comparison to healthy controls (n=20). In add
ition, patients with fibromyalgia showed decreased levels of calcitoni
n and prostaglandin E2 compared to controls. On the other hand, decrea
sed levels of oxytocin were found in patients with major depression if
compared to controls. Further investigations will be needed to confir
m these results, especially with regard to sensitivity and specificity
.