MOLECULAR-CLONING OF A NOVEL MESSENGER-RNA (HARDERIN) SPECIFICALLY AND HIGHLY EXPRESSED IN THE HARDERIAN-GLAND OF THE FROG, RANA-ESCULENTA

Citation
F. Aniello et al., MOLECULAR-CLONING OF A NOVEL MESSENGER-RNA (HARDERIN) SPECIFICALLY AND HIGHLY EXPRESSED IN THE HARDERIAN-GLAND OF THE FROG, RANA-ESCULENTA, Biochemistry and molecular biology international, 38(2), 1996, pp. 401-408
Citations number
10
Categorie Soggetti
Biology
ISSN journal
10399712
Volume
38
Issue
2
Year of publication
1996
Pages
401 - 408
Database
ISI
SICI code
1039-9712(1996)38:2<401:MOANM(>2.0.ZU;2-K
Abstract
A cDNA clone encoding a novel mRNA (harderin) has been isolated from t he cDNA library of frog Rana esculenta Harderian gland. The cDNA is 87 5 bp long and encodes a novel protein of 218 amino acid residues. The deduced proteins reveals no significant homology to other proteins. Th e mRNA is a single 0.9 kb transcript detected only in the RNA of frog Harderian gland, highly expressed throughout the year. The constant an d exclusive presence of harderin in the frog Harderian gland, suggests a constitutive tissue specific expression for this protein.