Y. Kuge et H. Kawashima, [1-C-11]OCTANOATE AS A POTENTIAL PET TRACER FOR STUDYING GLIAL FUNCTIONS - PET EVALUATION IN RATS AND CATS, Nuclear medicine and biology, 23(8), 1996, pp. 1009-1012
To evaluate the ability of [1-C-11]octanoate as a PET tracer for imagi
ng the brain, we examined its distribution in the brain and surroundin
g tissues in rats and cats with PET. In rats, owing to the accumulated
radioactivity in the harderian glands, clear brain images were not ob
tained at rostral levers. In cats, the brain was imaged clearly at eve
ry level of the coronal brain slices, suggesting the potential of [1-C
-11]octanoate for imaging the brain. Copyright (C) 1996 Elsevier Scien
ce Inc.