Cy. Guezennec, HORMONAL RESPONSES AND ADJUSTMENTS DURING SHORT-TERM EXERCISE AND PHYSICAL-TRAINING, La Semaine des hopitaux de Paris, 72(23-24), 1996, pp. 738-742
Physical activity mobilizes energy reserves to supply substrates for v
arious metabolic pathways. This phenomenon is partly regulated by horm
onal changes, of which the most important are a decrease in plasma ins
ulin and increases in catecholamine levels. The increase in sensitivit
y to insulin associated with physical activity allows the muscles to u
se larger amounts of glucose despite low serum insulin levels. The inc
reased sensitivity to insulin and the lipid profile changes induced by
physical training suggest that physical exercise may be effective in
preventing noninsulin dependent (Type II) diabetes mellitus. In contra
st, physical activity has no effect on the etiopathogenesis of insulin
dependent (Type I) diabetes mellitus. Physical training can act synerg
istically with dietary treatment in patients with obesity but is ineff
ective in the absence of an appropriate diet. Regular physical activit
y is among the lifestyle factors that can influence the development an
d course of metabolic diseases, provided that the level and duration o
f physical exercise are sufficient.