GRANULOCYTIC SARCOMA WITH EXPRESSION OF CD30

A case of a young man with a spinal epidural tumour, initially diagnos ed as large cell anaplastic malignant lymphoma, is reported. The tumou r consisted of poorly differentiated cells showing immunoreactivity wi th antibodies directed against CD30 and CD45. Ten months later the pat ient developed acute myeloid leukaemia. The histological slides of the epidural tumour were reviewed, including additional enzymochemical an d immunochemical stains. As the tumour showed immunoreactivity for mye loperoxidase and chloroacetate esterase, it was reclassified as a gran ulocytic sarcoma.