QUANTITATIVE TLC FOR QUALITY-CONTROL OF DRUGS STORED LONG-TERM BY THEGERMAN FEDERAL ARMED-FORCES MEDICAL-SERVICE

Citation
W. Dammertz et H. Paulus, QUANTITATIVE TLC FOR QUALITY-CONTROL OF DRUGS STORED LONG-TERM BY THEGERMAN FEDERAL ARMED-FORCES MEDICAL-SERVICE, JPC. Journal of planar chromatography, modern TLC, 8(4), 1995, pp. 314-318
Citations number
9
Categorie Soggetti
Chemistry Analytical
ISSN journal
09334173
Volume
8
Issue
4
Year of publication
1995
Pages
314 - 318
Database
ISI
SICI code
0933-4173(1995)8:4<314:QTFQOD>2.0.ZU;2-L
Abstract
The supply of drugs to an army in action is extremely important, and a sufficient quantity of these drugs must, therefore, be stocked in med ical depots. According to German drug law, the FAF Medical Service is responsible for ensuring the quality of these drugs. The analysis of c hloramphenicol-monosuccinate and gentamycin is presented as an example of the use of quantitative TLC for quality control both of freshly pr oduced drugs and those stored long-term. In order to increase the effe ctiveness of the drug quality assurance system of the FAF Medical Serv ice, screening methods, mainly employing TLC, were developed for the a nalysis of formulated drugs in medical depots. The test design and met hod development are also presented.