Agger nasi cells contribute to nasofrontal duct (NFD) obstruction and
chronic frontal sinus disease. To investigate this relationship, we co
nducted a review of the surgical outcome and computed tomographic imag
ing in 26 patients with chronic frontal sinusitis. Coronal and sagitta
l images were used to delineate the anatomic variability and mucosal d
isease in the NFD and frontal sinus region. Data from coronal and sagi
ttal images were compared. The results were also correlated with the o
utcome of frontal sinus surgery in patients with a clinical history of
chronic frontal sinus disease. Our data suggest that agger nasi cell
pneumatization with narrowing of the frontal sinus outflow tract is a
significant cause of persistent frontoethmoid pain and chronic frontal
sinusitis. Sagittal reformatted images are more capable than coronal
images of demonstrating agger nasi cell encroachment on the NFD, as we
ll as NFD mucosal disease. Endoscopic frontal sinusotomy is an effecti
ve treatment for chronic frontal sinus disease.