MEDIASTINAL YOLK-SAC TUMOR IN A YOUNG GIRL - CASE-REPORT AND REVIEW OF THE LITERATURE

The authors report a rare case of a female infant who underwent succes sful treatment of a mediastinal yolk sac tumor, Therapy included four cycles of preoperative PVB (cisplatinum, vinblastine, bleomycin), comp lete surgical resection of the tumor, and one postoperative cycle of P VB and four cycles of VAC (vincristine, actinomycine, cyclophosphamide ) chemotherapy. The successful treatment of this tumor depends on preo perative chemotherapy to reduce the size, followed by complete surgica l excision with subsequent postoperative chemotherapy. Recent improvem ents in the treatment of mediastinal yolk sac tumors are discussed. Co pyright (C) 1996 by W.B. Saunders Company