MAPPING OF THE H7-SEROSPECIFIC DOMAIN OF ESCHERICHIA-COLI FLAGELLIN

Authors
KWANG J WILSON R YANG S HE YS
Citation
J. Kwang et al., MAPPING OF THE H7-SEROSPECIFIC DOMAIN OF ESCHERICHIA-COLI FLAGELLIN, Clinical and diagnostic laboratory immunology, 3(5), 1996, pp. 523-526
Citations number
22
Categorie Soggetti
Immunology,"Infectious Diseases","Medical Laboratory Technology",Microbiology
Journal title
Clinical and diagnostic laboratory immunology → ACNP
ISSN journal
1071412X
Volume
3
Issue
5
Year of publication
1996
Pages
523 - 526
Database
ISI
SICI code
1071-412X(1996)3:5<523:MOTHDO>2.0.ZU;2-F
Abstract
The amino acid sequences responsible for H7 and H23 flagellum serology have been identified by using a genetic approach. The H7-specific dom ain was located between amino acids 352 and 374 of the H7 flagellin. T he sequencing data also demonstrated that the difference between the H 7 and H23 flagellins in this region results from a single substitution at amino acid 366 (Ser-->Thr). The common epitopes for H7 and H23 wer e located between amino acids 284 and 366.