INTESTINAL MOTILITY AFTER MASSIVE SMALL-BOWEL RESECTION IN CONSCIOUS CANINES - COMPARISON OF ACUTE AND CHRONIC PHASES

Citation
M. Uchiyama et al., INTESTINAL MOTILITY AFTER MASSIVE SMALL-BOWEL RESECTION IN CONSCIOUS CANINES - COMPARISON OF ACUTE AND CHRONIC PHASES, Journal of pediatric gastroenterology and nutrition, 23(3), 1996, pp. 217-223
Citations number
25
Categorie Soggetti
Gastroenterology & Hepatology","Nutrition & Dietetics",Pediatrics
ISSN journal
02772116
Volume
23
Issue
3
Year of publication
1996
Pages
217 - 223
Database
ISI
SICI code
0277-2116(1996)23:3<217:IMAMSR>2.0.ZU;2-0
Abstract
To evaluate intestinal function after 80% massive distal small bowel r esection (MSBR), we continuously monitored interdigestive and postpran dial bowel motility using bipolar electrodes and/or contractile strain gauge force transducers in conscious beagle dogs before and at 2-4 we eks (acute postoperative phase; acute phase) and 8-13 months (chronic postoperative phase; chronic phase) after the surgery. Fasting duodena l migrating myoelectric (or motor) complexes (MMC) occurred at longer intervals in the acute phase after 80% MSBR than in control beagles. I ntervals between duodenal MMC in the chronic phase were similar to tho se found in control beagles. MMC arising from the duodenum were often interrupted before the jejunum above the anastomosis in the acute phas e, and a slight recovery of propagation frequency to the jejunum above the anastomosis was observed in the chronic phase. However, duodenal MMC did not migrate smoothly to the terminal ileum in both groups. In the acute phase, the velocity of duodenal MMC propagation was slowed i n every intestinal segment, including the duodenum and the jejunum abo ve the anastomosis, and had not recovered even long after the operatio n. The duration of the postprandial period without duodenal MMC was pr olonged significantly in the acute phase postoperatively. Although it shortened in the chronic phase, it still remained significantly longer than in controls. These findings suggest that changes in gut motility after MSBR tend to compensate for the shorter intestine and maintain small bowel absorption early postoperatively. However, these compensat ory changes decrease over the long term, and their adaptive contributi ons to increased intestinal absorption may decrease as well.