The standard modality to treat colorectal cancer in potentially curabl
e patients is, undoubtedly, surgery. The concept of precautional chemo
therapy used in tumors located elsewhere, has put forward a clinical t
rial that proved its effectiveness and improved survival, We report th
e use of two modalities (chemotherapy and radiotherapy) along with sur
gery as part of a multidisciplinary treatment of patients with colorec
tal cancer.