Jp. Lindenmayer et al., COGNITIVE DEFICITS AND PSYCHOPATHOLOGY IN ELDERLY SCHIZOPHRENIC-PATIENTS, The American journal of geriatric psychiatry, 5(1), 1997, pp. 31-42
The authors investigated the syndromal and cognitive profiles of 25 DS
M-III-R older schizophrenic inpatients with continuous acute psychotic
symptoms and compared them with 20 younger schizophrenic patients by
means of a multidimensional assessment battery. Subjects were medicall
y well and without neurological comorbidity and were comparable in len
gth of current hospitalization and medication regimens. There were no
significant differences between the two groups on various symptom rati
ng scores or on neurological variables. The older group's mean scores
for various cognitive measures did not reach the value for senile deme
ntia. They also scored significantly better on a memory test and on fo
rmal cognitive functions. These findings support the notion of a stabl
e encephalopathy, rather than a dementia-like process, underlying the
course of the illness. Authors discussed limitations and implications
of these findings.