CLONING AND SEQUENCE-ANALYSIS OF AN INTRON-CONTAINING DOMAIN FROM A PEPTIDE SYNTHETASE-ENCODING GENE OF THE ENTOMOPATHOGENIC FUNGUS METARHIZIUM-ANISOPLIAE

Authors
BAILEY AM KERSHAW MJ HUNT BA PATERSON IC CHARNLEY AK REYNOLDS SE CLARKSON JM
Citation
Am. Bailey et al., CLONING AND SEQUENCE-ANALYSIS OF AN INTRON-CONTAINING DOMAIN FROM A PEPTIDE SYNTHETASE-ENCODING GENE OF THE ENTOMOPATHOGENIC FUNGUS METARHIZIUM-ANISOPLIAE, Gene, 173(2), 1996, pp. 195-197
Citations number
13
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
173
Issue
2
Year of publication
1996
Pages
195 - 197
Database
ISI
SICI code
0378-1119(1996)173:2<195:CASOAI>2.0.ZU;2-P
Abstract
A gene encoding a putative peptide synthetase has been cloned and part ially sequenced from the filamentous fungus, Metarhizium anisopliae. T he deduced amino acid sequence of one entire domain and the following spacer is typical of fungal peptide synthetases, showing good conserva tion of the six expected core sequences. There are two introns within this region, the first interrupting core 5 (RLDLTDIE) of the domain an d the second in a conserved area of the spacer region.