COEXISTENCE OF DIFFUSE PLANE NORMOLIPEMIC XANTHOMA AND AMYLOIDOSIS INA PATIENT WITH MONOCLONAL GAMMOPATHY

Diffuse plane normolipaemic xanthomatosis (DPNX) is a well-defined cli nicopathological entity that characteristically presents with yellow-o range plaques in the periorbital areas, the neck, the upper trunk and the flexural folds. DPNX has been reported in association with lymphop roliferative disorders and, occasionally, with miscellaneous, probably coincidental disorders, A case of DPNX in a patient with an IgG lambd a monoclonal gammopathy and systemic amyloidosis is reported, Clinical and histopathological findings revealed typical features of DPNX and amyloidosis coexisting in the cutaneous lesions. To our knowledge this is the first reported case showing coexistence of xanthoma and amyloi dosis in cutaneous lesions in a patient with a monoclonal gammopathy.