IN-VIVO AND IN-VITRO EFFECT OF AN ORGANOPHOSPHOROUS PESTICIDE, MONOCROTOPHOS ON ACETYLCHOLINESTERASE ACTIVITY IN WISTAR RATS

Authors
RAMESH N MURTHY PB PILLAI KS
Citation
N. Ramesh et al., IN-VIVO AND IN-VITRO EFFECT OF AN ORGANOPHOSPHOROUS PESTICIDE, MONOCROTOPHOS ON ACETYLCHOLINESTERASE ACTIVITY IN WISTAR RATS, Journal of environmental biology, 17(3), 1996, pp. 235-238
Citations number
15
Categorie Soggetti
Environmental Sciences
Journal title
Journal of environmental biology → ACNP
ISSN journal
02548704
Volume
17
Issue
3
Year of publication
1996
Pages
235 - 238
Database
ISI
SICI code
0254-8704(1996)17:3<235:IAIEOA>2.0.ZU;2-K
Abstract
Acetylcholinesterase activity was determined in blood, brain, liver an d kidney of rats in vivo and in vitro after treating with an O.P. pest icide, monocrotophos (36% SL) at the median lethal dose. The observati ons showed, in vivo decrease in activity is faster than in vitro. More over brain is the first organ to be affected both in vivo and in vitro and blood and brain AchE can be taken as a marker for both in vivo an d in vitro.