HIGHER CEREBRAL-DYSFUNCTION IN A CASE WITH ATYPICAL MULTIPLE-SCLEROSIS WITH CONCENTRIC LESIONS

A patient with atypical multiple sclerosis (MS) with clear concentric structure was studied using high field magnetic resonance imaging (MRI ). This case was considered to be Bald's concentric sclerosis. Magneti c resonance imaging showed diffuse multiple concentric demyelinating l esions in the bilateral centrum semiovales, which finally regressed wi th the necrotic lesions remaining when the patient was discharged. Dur ing his clinical course, he showed some higher cerebral dysfunctions, such as memory disturbance, constructual apraxia and acalculia. He was treated with glycerin, prednisone and rehabilitation; all of which we re effective in his recovery. Over a 4 month period, the patient recov ered clinically, but some intellectual impairment remained.