Objectives. To determine the safety and efficacy of transurethral elec
trovaporization of the prostate (TVP) in men with lower urinary tract
symptoms. Methods. A prospective trial of 114 consecutive patients who
underwent TVP since August 1994 was conducted. The mean follow-up per
iod was 12.3 months. Parameters evaluated included American Urological
Association symptom score (Sx), peak urinary flow rate (Qmax), operat
ive time, postoperative catheterization time, length of hospital stay,
and loss of days from work. Results. Of the 109 men available for fol
low-up, Sx decreased from 16.7 to 7.3, 6.5, 6.3, and 5.4 at 3, 6, 12,
and 18 months, respectively (P <0.001), whereas Qmax increased from 7.
9 to 14.8, 15.6, 16.7, and 16.5 mL/s at 3, 6, 12, and 18 months, respe
ctively (P <0.001). Mean catheterization time was 10.4 hours; mean hos
pital period was 0.9 days, and average loss of days from work was 5.6.
Complications included intermittent postoperative hematuria in 65 pat
ients (57%), clot retention in 6 (5%), and bulbar urethral stricture i
n 2 (2%). Of 74 men who were potent preoperatively, none had postopera
tive erectile dysfunction; retrograde ejaculation was noted in 62 (84%
). Significant postoperative irritative symptoms were reported in 10 m
en (9%). Conclusions. On the basis of 1-year follow-up data, this stud
y demonstrates that TVP is a safe and effective modality for treating
lower urinary tract symptoms. However, longer, prospective, blinded st
udies are needed to determine efficacy relative to transurethral resec
tion of the prostate. Copyright 1996 by Elsevier Science Inc.