Superior vena cava syndromes are uncommon and usually caused by malign
ant diseases. In about 20% of the cases however, the cause is benign.
Besides chronic mediastinitis, a growing number of cases are reported
of thrombosis resulting from endovenous devices (central catheters, pa
cemaker leads...). Onset is often slow and insidious, good tolerance i
n the early stages being explained by the development of an effective
collateral circulation. Bibrachial phlebography is still the reference
exploration, but computed tomography and magnetic resonance imaging a
re contributive to diagnosis. Symptoms usually regress after medical t
reatment, sometimes requiring thrombolysis, however, in 10% of the pat
ients, major functional impairment may require bypass surgery (autolog
ous graft or endoprosthesis) or transluminal angioplasty. There is sti
ll some debate as to the precise indications for each method, but angi
oplasty, used recently, appears to be the most interesting technique f
or a disease in which prognosis is almost always favorable.