MOLECULAR-STRUCTURE AND FUNGICIDAL ACTIVITY AGAINST CERATOCYSTIS-ULMIOF THE 1 1 ADDUCTS OF TRIPHENYLTIN CHLORIDE AND 2,3-DISUBSTITUTED THIAZOLIDIN-4-ONES/

Several 1:1 addition compounds between triphenyltin chloride and 2,3-d isubstituted thiazolidin-4-one ligands have been synthesized. Their mo lecular structure has been deduced using far IR and Mossbauer spectros copies, In addition, molecular modeling of several of the complexes wa s used to explain the variation of the quadrupole splitting values in the Mossbauer spectra, The structures of the complexes were determined to be trigonal-bipyramidal with the three phenyl groups in the equato rial plane, However, the phenyl groups are not co-planar, on the basis of the observation of both the Sn-C (phenyl) symmetric and asymmetric stretching vibrations, The adducts were screened against the fungus C eratocystis ulmi, the agent responsible for Dutch elm disease, and fou nd to be effective in the inhibition of this fungus, The toxicity of t he adducts varied with the hydrophobicity of the molecule, A direct co rrelation between substitution on the phenyl group on the thiazolidine ring and the toxicity of the compound was not observed.