DIORGANOTIN(IV) COMPLEXES OF SOME SCHIFF-BASES WITH IS POTENTIAL BIOLOGICAL-ACTIVITY

Diorganotin dichloride compounds, R(2)SnCl(2) (R=Me, nBu, Ph) react wi th Schiff bases (L), derived from substituted and non-substituted 2- o r 3-aminopyridine with 2-hydroxy-, 2-methoxy- or 2-hydroxy-3-methoxy-b enzaldehyde in a 1:1 molar ratio, to give complexes of general formula R(2)SnCl(2) . L. It is suggested that the Schiff bases coordinate wit h tin in bidentate fashion to give hexacoordinate tin species, Almost all the complexes prepared show some 1 : 1 molar conductivity in ethan ol and DMF, indicating an [R(2)Sn(L)Cl](+) Cl- ionic structure type, T he complexes were screened against seven species of bacteria.