NEUROMYOTONIA AND TYPE-I MYOFIBER PREDOMINANCE IN AMYLOIDOSIS

Citation
L. Gutmann et al., NEUROMYOTONIA AND TYPE-I MYOFIBER PREDOMINANCE IN AMYLOIDOSIS, Muscle & nerve, 19(10), 1996, pp. 1338-1341
Citations number
16
Categorie Soggetti
Neurosciences
Journal title
ISSN journal
0148639X
Volume
19
Issue
10
Year of publication
1996
Pages
1338 - 1341
Database
ISI
SICI code
0148-639X(1996)19:10<1338:NATMPI>2.0.ZU;2-3
Abstract
A case of amyloidosis presented with neuromyotonia and marked predomin ance of type I myofibers as documented by biopsy of an enlarged anteri or tibialis muscle. This likely represents conversion of type II fiber s to type from continuous neuromyotonic stimulation. This transformati on is well described to occur in animal models and this case represent s a unique human example. Enlarged muscles likely reflected pseudohype rtrophy. (C) 1996 John Wiley & Sons, Inc.