2 CASES OF KAPOSIS-SARCOMA IN RENAL AND LIVER-TRANSPLANT RECIPIENTS TREATED WITH INTERFERON

We report two cases of Kaposi's sarcoma in recipients of solid organ t ransplants, presenting (Case 1) 12 months after liver transplantation and (Case 2) 7 months after kidney transplantation. Both patients shar e the following features: natives from the Mediterranean area (Souther n Italy), multiple immunosuppressive regimen, infection with hepatitis B and cytomegalovirus. During the 3 yr of follow-up after the diagnos is their immunosuppressive regimen was reduced and they were treated w ith alpha interferon with remission of the clinical findings. The mana gement of Kaposi's sarcoma in organ transplant recipients remains a co ntroversial issue because of the risks of organ rejection associated w ith the reduction of immunosuppression and with the use of interferon.